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Title: Dietary patterns in relation to cardiovascular disease incidence and risk markers in a middle-aged British male population: data from the Caerphilly Prospective Study.
Authors: Mertens, Elly
Markey, Oonagh
Geleijnse, Johanna M.
Givens, David Ian
Lovegrove, Julie A.
Keywords: Dietary patterns
Principal component analysis
Cardiovascular incidence
Cardiovascular risk markers
Caerphilly Prospective Study (CaPS)
Issue Date: 2017
Publisher: © The Authors. Published by MDPI.
Citation: MERTENS, E. ...et al., 2017. Dietary patterns in relation to cardiovascular disease incidence and risk markers in a middle-aged British male population: data from the Caerphilly Prospective Study.. Nutrients, 9(1): 75.
Abstract: Dietary behaviour is an important modifiable factor in cardiovascular disease (CVD) prevention. The study aimed to identify dietary patterns (DPs) and explore their association with CVD incidence and risk markers. A follow-up of 1838 middle-aged men, aged 47–67 years recruited into the Caerphilly Prospective Cohort Study at phase 2 (1984–1988) was undertaken. Principal component analysis identified three DPs at baseline, which explained 24.8% of the total variance of food intake. DP1, characterised by higher intakes of white bread, butter, lard, chips and sugar-sweetened beverages and lower intake of wholegrain bread, was associated with higher CVD (HR 1.35: 95% CI: 1.10, 1.67) and stroke (HR 1.77; 95% CI: 1.18, 2.63) incidence. DP3, characterised by higher intakes of sweet puddings and biscuits, wholegrain breakfast cereals and dairy (excluding cheese and butter) and lower alcohol intake, was associated with lower CVD (HR 0.76; 95% CI: 0.62, 0.93), coronary heart disease (HR: 0.68; 95% CI: 0.52, 0.90) and stroke (HR: 0.68; 95% CI: 0.47, 0.99) incidence and a beneficial CVD profile at baseline, while DP1 with an unfavourable profile, showed no clear associations after 12 years follow-up. Dietary pattern 2 (DP2), characterised by higher intake of pulses, fish, poultry, processed/red meat, rice, pasta and vegetables, was not associated with the aforementioned outcomes. These data may provide insight for development of public health initiatives focussing on feasible changes in dietary habits.
Description: This is an Open Access Article. It is published by MDPI under the Creative Commons Attribution 4.0 Unported Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/4.0/
Sponsor: This work was supported by a research grant from the Dutch Heart Foundation (E. Dekker scholarship).
Version: Published
DOI: 10.3390/nu9010075
URI: https://dspace.lboro.ac.uk/2134/24059
Publisher Link: http://dx.doi.org/10.3390/nu9010075
ISSN: 2072-6643
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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