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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/25266

Title: A biosynthetically inspired route to substituted furans using the Appel reaction: total synthesis of the furan fatty acid F5
Authors: Lee, Robert J.
Lindley, Martin R.
Pritchard, Gareth J.
Kimber, Marc C.
Issue Date: 2017
Publisher: © Royal Society of Chemistry
Citation: LEE, R.J. ...et al., 2017. A biosynthetically inspired route to substituted furans using the Appel reaction: total synthesis of the furan fatty acid F5. Chemical Communications, 53 (47), pp. 6327-6330.
Abstract: Appel reaction conditions have been harnessed to affect a mild biosynthetically inspired dehydration of endoperoxides to deliver multi-substituted electron rich furans. Unlike traditional dehydrative procedures, this method is metal and acid free, and can be achieved under redox neutral conditions. It is general for a range of aryl and alkyl substituted endoperoxides, and is functional group tolerant. Furthermore, this procedure has been used to deliver an effective total synthesis of the furan fatty acid (FFA) F5.
Description: This paper is in closed access until 19th May 2018.
Version: Accepted for publication
DOI: 10.1039/C7CC03229C
URI: https://dspace.lboro.ac.uk/2134/25266
Publisher Link: http://dx.doi.org/10.1039/C7CC03229C
ISSN: 0009-241X
Appears in Collections:Closed Access (Chemistry)

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