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Title: Localized and systemic variations in central motor drive at different local skin and muscle temperatures
Authors: Lloyd, Alex
Picton, Lewis
Raccuglia, Margherita
Hodder, S.G.
Havenith, George
Issue Date: 2017
Publisher: © American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Citation: LLOYD, A. ... et al., 2017. Localized and systemic variations in central motor drive at different local skin and muscle temperatures. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 313(3), pp.R219-228.
Abstract: This study investigated the ability to sustain quadriceps central motor drive while subjected to localized heat and metaboreceptive feedback from the contralateral leg. Eight active males each completed two counter-balanced trials, in which muscle temperature (Tm) of a single-leg (TEMP-LEG) was altered to 29.4 (COOL) or 37.6°C (WARM), while the contralateral leg (CL-LEG) remained thermoneutral; 35.3 and 35.2°C Tm in COOL and WARM respectively. To activate metaboreceptive feedback, participants first performed one 120-s isometric maximal voluntary contraction (MVC) of the knee extensors in the TEMP-LEG, immediately followed by post-exercise muscle ischemia (PEMI) via femoral blood flow occlusion. To assess central motor drive of a remote muscle group immediately following PEMI, another 120-s MVC was subsequently performed in the CL-LEG. Voluntary muscle activation (VA) was assessed using the twitch interpolation method. Perceived mental effort and limb discomfort were also recorded. In a cooled muscle, a significant increase in mean force output and mean VA (force, p<0.001; VA, p<0.05) as well as a significant decrease in limb discomfort (p<0.05) occurred during the sustained MVC in the TEMP-LEG. However, no differences between Tm were observed in mean force output, mean VA or limb discomfort during the sustained MVC in the CL-LEG (Force, p=0.33; VA, p>0.68, limb discomfort, p=0.73). The present findings suggest that elevated local Tsk and Tm can increase limb discomfort and decrease central motor drive, but this does not limit systemic motor activation of a thermoneutral muscle group.
Description: This article was published in the AJP - Regulatory, Integrative and Comparative Physiology [© APS] and the definitive version is available at: https://doi.org/10.1152/ajpregu.00055.2017
Version: Accepted for publication
DOI: 10.1152/ajpregu.00055.2017
URI: https://dspace.lboro.ac.uk/2134/25380
Publisher Link: http://dx.doi.org/10.1152/ajpregu.00055.2017
ISSN: 0363-6119
Appears in Collections:Published Articles (Design School)

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