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Title: Tofu intake is associated with poor cognitive performance among community-dwelling elderly in China
Authors: Xu, Xin
Xiao, Shifu
Rahardjo, T.B.
Hogervorst, Eef
Keywords: China
Issue Date: 2015
Publisher: © The Authors. Published by IOS
Citation: XU, X. ...et al., 2015. Tofu intake is associated with poor cognitive performance among community-dwelling elderly in China. Journal of Alzheimer's Disease, 43(2), pp. 669-675.
Abstract: © 2015 IOS Press and the authors. All rights reserved.Tofu is a soy product which is commonly consumed in Asian countries, such as China and Indonesia. Several studies found negative associations of high tofu consumption with cognitive function in older Asian populations. However, the effect of tofu on cognitive function remains disputed as it was not found in Western populations. In the present study, the effect of weekly tofu intake on cognitive performance was investigated in an observational cross sectional study of 517 Chinese elderly from Shanghai. Similar to earlier studies, results showed that a higher weekly intake of tofu was associated with worse memory performance using the Hopkins Verbal Learning Test (β =-0.10, p = 0.01) after controlling for age, gender, education, being vegetarian, and weekly intake of fruit/juice, green vegetables, and orange/red vegetables. Furthermore, among older elderly (≥68 years of age), high tofu intake increased the risk of cognitive impairment indicative of dementia (OR = 1.27, 95% CI = 0.99-1.64, p = 0.04), after adjusting for all covariates. Consumption of meat and green vegetables independently also reduced risk of dementia. To conclude, high intake of tofu was negatively related to cognitive performance among community-dwelling elderly in China. Similar findings were reported in Indonesia and in Japanese Americans in the US. These findings suggest that the effect of tofu on cognition in elderly should be further investigated.
Description: The final publication is available at IOS Press through http://dx.doi.org/10.3233/JAD-141593
Sponsor: This study was funded by China Science and Technology Ministry.
Version: Submitted for publication
DOI: 10.3233/JAD-141593
URI: https://dspace.lboro.ac.uk/2134/25621
Publisher Link: http://dx.doi.org/10.3233/JAD-141593
ISSN: 1387-2877
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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