Thesis-1996-Sulaiman.pdf (3.68 MB)
New approaches to elemental speciation
thesis
posted on 2017-07-12, 15:49 authored by Azli B. SulaimanElemental speciation has been one of the principal growth areas in analytical atomic
spectrometry. This reflects the recognition that in the environmental and biological
sciences, the transport, pool dynamics and toxicology of the elements are dependent
on their chemical speciation. Significant progress has been made in elemental
speciation by the direct coupling of separation techniques, notably the various forms
of chromatography, to powerful elemental detectors such as ICP-MS. However, the
strength of such hyphenated techniques, that they provide almost unambiguous
identification of elemental associations, is often achieved at the expense of losing
information about the ligands that are responsible for the speciation. The challenge
must be to bring the two approaches to bear simultaneously so that quantitative and
qualitative information on both the inorganic and organic components can be
obtained simultaneously.
Capillary electrophoresis (CE) has developed into one of the most powerful
separation techniques offering rapid separations with high resolution. However, these
advantages are offset by low sensitivity which is a consequence of the very small (nl)
samples that the technique can handle. These problems can be overcome by using
high sensitivity detectors and hence the interest in coupling CE to .ICP-MS. Coupling
of CE to ICP-MS (CE-ICP-MS) has, therefore, the potential to provide rapid and
quantitative elemental speciation information that is complementary to that provided
by other techniques. This thesis describes an interface for coupling CE to ICP-MS
and its applications to some common metal species. A particular interest in this work
has been to investigate the potential of CE for studying metal complexes with humic
and fulvic acids.
A technique that offers potential for determining both free element and complexed
forms, without prior separation IS electrospray/ion spray ionisation-mass
spectrometry. Preliminary work is presented that investigates the applications of
electrospray/ion spray ionisation-mass spectrometry to some common metal-ligand
systems.
History
School
- Science
Department
- Chemistry
Publisher
© Azli Bin SulaimanPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
1996Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy of Loughborough University.Language
- en