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Title: A quantitative, multi-national and multi-stakeholder assessment of barriers to the adoption of cell therapies
Authors: Davies, Ben
Smith, James
Rikabi, Sarah
Wartolowska, Karolina
Morrey, Mark
French, Anna
MacLaren, Robert
Williams, David J.
Bure, Kim
Pinedo-Villanueva, Rafael
Mathur, Anthony
Birchall, Martin
Snyder, Evan
Atala, Anthony
Reeve, Brock
Brindley, David
Keywords: Cell- and tissue-based therapy
Regenerative medicine
Stem cells
Translational medical research
Clinical adoption
Issue Date: 2017
Publisher: SAGE © The Author(s)
Citation: DAVIES, B. ... et al, 2017. A quantitative, multi-national and multi-stakeholder assessment of barriers to the adoption of cell therapies. Journal of Tissue Engineering, 8, pp. 1-8.
Abstract: Cellular therapies, such as stem cell–based treatments, have been widely researched and numerous products and treatments have been developed. Despite this, there has been relatively limited use of these technologies in the healthcare sector. This study sought to investigate the perceived barriers to this more widespread adoption. An anonymous online questionnaire was developed, based on the findings of a pilot study. This was distributed to an audience of clinicians, researchers and commercial experts in 13 countries. The results were analysed for all respondents, and also sub-grouped by geographical region, and by profession of respondents. The results of the study showed that the most significant barrier was manufacturing, with other factors such as efficacy, regulation and cost-effectiveness being identified by the different groups. This study further demonstrates the need for these important issues to be addressed during the development of cellular therapies to enable more widespread adoption of these treatments.
Description: This is an Open Access Article. It is published by Sage under the Creative Commons Attribution 4.0 Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/4.0/
Sponsor: JS is funded by an MRC UK Studentship.
Version: Published
DOI: 10.1177/2041731417724413
URI: https://dspace.lboro.ac.uk/2134/26435
Publisher Link: https://doi.org/10.1177/2041731417724413
ISSN: 2041-7314
Appears in Collections:Published Articles (Mechanical, Electrical and Manufacturing Engineering)

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