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Loughborough University

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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/27412

Title: The synthesis of novel agents which inhibit tumour-stimulated bone resorption
Authors: Mansfield, Ian D.
Issue Date: 1999
Publisher: © Ian Mansfield
Abstract: A range of conjugates which focused on bisphosphonates as delivery molecules and on oestrogens as resorption inhibitors were synthesised. Various moieties were coupled through an ester linkage to bisphosphonates which were then converted to the corresponding bisphosphonic acids. This ester linkage was considered to be readily hydrolysable under normal physiological conditions. [Continues.]
Description: A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.
URI: https://dspace.lboro.ac.uk/2134/27412
Appears in Collections:PhD Theses (Chemistry)

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