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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/27489

Title: Physical activity pre- and post-dementia: English Longitudinal Study of Ageing
Authors: Soni, Mira
Orrell, Martin
Bandelow, Stephan
Steptoe, Andrew
Rafnsson, Snorri Bjorn
d'Orsi, Eleonora
Xavier, Andre Junqueira
Hogervorst, Eef
Keywords: Alzheimer’s disease
Other dementias
Epidemiology (Dementia)
Physical activity
Cognitive functioning
Issue Date: 2017
Publisher: © Taylor & Francis
Citation: SONI, M. ...et al., 2017. Physical activity pre- and post-dementia: English Longitudinal Study of Ageing. Aging and Mental Health, In Press.
Abstract: Background: To inform public health interventions, further investigation is needed to identify: (1) frequency/intensity of everyday physical activity (PA) needed to reduce dementia risk; (2) whether post-diagnosis reduction in PA is associated with cognitive outcomes in people with dementia. Methods: Data from 11,391 men and women (aged ≥50) were obtained from the English Longitudinal Study of Ageing cohort. Assessments were carried out at baseline (2002–2003) and at biannual follow-ups (2004–2013). Results: Older adults who carried out moderate to vigorous activity at least once per week had a 34%–50% lower risk for cognitive decline and dementia over an 8–10 year follow-up period. From pre- to post-dementia diagnosis, those who decreased PA levels had a larger decrease in immediate recall scores, compared to those who maintained or increased PA levels (analyses were adjusted for changes in physical function). Conclusion: PA was associated with cognitive outcomes in a dose-dependent manner. Reduction in PA after diagnosis was associated with accelerated cognitive decline and maintaining PA may reduce symptom progression in dementia.
Description: This is an Accepted Manuscript of an article published by Taylor & Francis in Aging and Mental Health on 17 Oct 2017, available online: https://doi.org/10.1080/13607863.2017.1390731.
Sponsor: This study was carried out as part of PRIDE (PRomoting Independence in DEmentia). PRIDE was funded by the UK Economic and Social Research Council (ESRC) (Grant ES/L001802/1).
Version: Accepted for publication
DOI: 10.1080/13607863.2017.1390731
URI: https://dspace.lboro.ac.uk/2134/27489
Publisher Link: https://doi.org/10.1080/13607863.2017.1390731
ISSN: 1360-7863
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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