SHIPILOVSKIKH, S.A., RUBTSOV, A.E. and MALKOV, A.V., 2017. Oxidative dehomologation of aldehydes with oxygen as a terminal oxidant. Organic Letters, 19(24), pp. 6760-6762.
A mild, efficient protocol for oxidative cleavage of C-C bond in aldehydes has been developed that employs alkali metal hydrides as reagents and oxygen from air as a terminal oxidant. The method is applicable to a broad substrate range.
This paper is in closed access until Nov 28th 2018.
The authors thank Russian Science Foundation for grant 15-13-00092.