Ultrafiltration of bovine blood plasma

An evaluation of the pilot-scale ultrafiltration of bovine blood plasma was conducted using tubular cellulose acetate membranes in a Paters on Candy International ultra-filtration unit. The effects on ultrafiltration of various operating parameters were studied including plasma feed pressure over the range 3.3 to 8.4 kg cm-2 mean feed pressure, feed temperature over the range 20 to 45°C and feed flow rate over the range 7.5 to 15.51 min-1. Trials were carried out maintaining feed composition constant at about 60 mg ml-1 protein concentration followed by studying the effects on ultrafiltration of plasma concentrations up to about 150 mg ml-1 protein concentration. [Continues.]