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|Title: ||The positive association of infant weight gain with adulthood body mass index has strengthened over time in the Fels Longitudinal Study|
|Authors: ||Lucas, Kimberly|
Choh, Audrey C.
Czerwinski, Stefan A.
Demerath, Ellen W.
Johnson, William O.
|Keywords: ||Infant weight gain|
Adulthood body mass index
Adulthood blood pressure
Birth cohort study
|Issue Date: ||2018|
|Publisher: ||© World Obesity Federation. Published by Wiley|
|Citation: ||LUCAS, K., 2018. The positive association of infant weight gain with adulthood body mass index has strengthened over time in the Fels Longitudinal Study. Pediatric Obesity, In Press.|
Infant weight gain is positively related to adulthood body mass index (BMI), but it is unknown whether or not this association is stronger for individuals born during (compared to before) the obesity epidemic.
To examine how the infant weight gain–adulthood BMI association might have changed across successive birth year cohorts spanning most of the 20th century.
The sample comprised 346 participants in the Fels Longitudinal Study. Confounder-adjusted regression models were used to test the associations of conditional weight-for-length Z-score (WLZ), capturing weight change between ages 0-2 years, with young adulthood BMI and blood pressure, including cohort (1933-1949 (N=137), 1950-1969 (N=108), 1970-1997 (N=101)) as an effect modifier.
Conditional WLZ was positively related to adulthood BMI, but there was significant effect modification by birth year cohort such that the association was over two times stronger in the 1970-1997 cohort (β 2.31; 95% confidence interval 1.59, 3.03) compared to the 1933-1949 (0.98; 0.31, 1.65) and 1950-1969 (0.87; 0.21, 1.54) cohorts. A similar pattern was found for systolic blood pressure.
The infant weight gain–adulthood BMI association was over two times stronger among a cohort born during the obesity epidemic era compared to cohorts born earlier in the 20th century.|
|Description: ||This paper is in closed access until 28 February 2019.|
|Version: ||Accepted for publication|
|Publisher Link: ||https://doi.org/10.1111/ijpo.12271|
|Appears in Collections:||Closed Access (Sport, Exercise and Health Sciences)|
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