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Title: Acetaminophen (Paracetamol) induces hypothermia during acute cold stress
Authors: Foster, Josh
Mauger, Alexis R.
Govus, Andrew
Hewson, David
Taylor, Lee
Issue Date: 2017
Publisher: © Springer
Citation: FOSTER, J. ...et al., 2017. Acetaminophen (Paracetamol) induces hypothermia during acute cold stress. Clinical Drug Investigation, 37(11), pp. 1055-1065.
Abstract: Background Acetaminophen is an over-the-counter drug used to treat pain and fever, but it has also been shown to reduce core temperature (Tc) in the absence of fever. However, this side effect is not well examined in humans, and it is unknown if the hypothermic response to acetaminophen is exacerbated with cold exposure. Objective To address this question, we mapped the thermoregulatory responses to acetaminophen and placebo administration during exposure to acute cold (10 °C) and thermal neutrality (25 °C).
Description: This is a post-peer-review, pre-copyedit version of an article published in Clinical Drug Investigation. The final authenticated version is available online at: https://doi.org/10.1007/s40261-017-0560-x
Version: Accepted version
DOI: 10.1007/s40261-017-0560-x
URI: https://dspace.lboro.ac.uk/2134/28351
Publisher Link: https://doi.org/10.1007/s40261-017-0560-x
ISSN: 1173-2563
Appears in Collections:Published Articles (Design School)

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