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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/28362

Title: A feasibility study to explore the governance processes required for linkage between dental epidemiological, and birth cohort, data in the UK
Authors: Day, Peter F.
Petherick, Emily S.
Godson, Jenny
Owen, Jenny
Douglas, Gail
Issue Date: 2018
Publisher: Dennis Barber Ltd
Citation: DAY, P.F. ... et al, 2018. A feasibility study to explore the governance processes required for linkage between dental epidemiological, and birth cohort, data in the UK. Community Dental Health, In Press.
Abstract: Birth cohort initiatives, such as ‘Born in Bradford’, provide a unique opportunity to study the influence of socio-economic and environmental factors acting in pregnancy, birth and infancy on the development of dental caries in later life. This paper describes a feasibility study which established the processes required, and outcomes of, successful linkage of oral health data collected by the 2013 three-year-old national dental epidemiology survey with the Born in Bradford birth cohort database. The necessary processes included achieving research permissions and ethical approval; creation of a data sharing agreement; ensuring data security and encrypted data transfer. With regard to the outcomes, a robust a priori statistical plan was developed. 152 three-year-old children were examined for the 2013 dental epidemiology survey in Bradford, and of those, 69 parents consented to data linkage believing that their child was part of the Born in Bradford cohort. However, only 36 of these 69 children were participating in the cohort. Of these, six children had obvious dentinal caries experience (dmft >0). There was insufficient power with such small numbers, to examine the association between birthweight and dental caries at the age of three-years-old. Key learning points from this feasibility study have informed the design of a larger study to link the 2014/5 five-year-old dental epidemiology surveys with the Born in Bradford cohort. This paper reveals the important methodological considerations for future data linkages between routine health data and research data.
Description: This paper appears here with the permission of the publisher. This paper was accepted for publication in the journal Community Dental Health published by Dennis Barber Ltd at http://www.cdhjournal.org/.
Sponsor: Oral and Dental Research Trust
Version: Accepted for publication
URI: https://dspace.lboro.ac.uk/2134/28362
Publisher Link: http://www.cdhjournal.org/
ISSN: 0265-539X
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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