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Title: First asymmetric synthesis of the natural enantiomer of the indolizidino[8,7-b]indole alkaloid harmicine
Authors: Allin, Steven M.
Gaskell, Sean N.
Elsegood, Mark R.J.
Martin, William P.
Issue Date: 2007
Publisher: © Elsevier
Citation: ALLIN, S.M ... et al, 2007. A new asymmetric synthesis of the natural enantiomer of the indolizidino[8,7-b]indole alkaloid (+)-harmicine. Tetrahedron letters, 48 (32), 6 August, pp. 5669-5671
Abstract: We report a novel, facile and asymmetric approach for the synthesis of the indole alkaloid harmicine via a highly diastereoselective N-acyliminium cyclization reaction as a key synthetic step, and verify the relative stereochemistry of the key synthetic intermediate in this approach through X-ray crystallography.
Description: This article was published in the journal, Tetrahedron letters [© Elsevier]. The definitive version is available at: http://www.sciencedirect.com/science/journal/00404039.
URI: https://dspace.lboro.ac.uk/2134/2891
ISSN: 0040-4039
Appears in Collections:Published Articles (Chemistry)

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