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| Title: | First asymmetric synthesis of the natural enantiomer of the indolizidino[8,7-b]indole alkaloid harmicine |
| Authors: | Allin, Steven M.
Gaskell, Sean N.
Elsegood, Mark R.J.
Martin, William P. |
| Issue Date: | 2007 |
| Publisher: | © Elsevier |
| Citation: | ALLIN, S.M ... et al, 2007. A new asymmetric synthesis of the natural enantiomer of the indolizidino[8,7-b]indole alkaloid (+)-harmicine.
Tetrahedron letters, 48 (32), 6 August, pp. 5669-5671 |
| Abstract: | We report a novel, facile and asymmetric approach for the synthesis of the indole alkaloid harmicine via a highly diastereoselective N-acyliminium cyclization reaction as a key synthetic step, and verify the relative stereochemistry of the key synthetic intermediate in this approach through X-ray crystallography. |
| Description: | This article was published in the journal, Tetrahedron letters [© Elsevier]. The definitive version is available at: http://www.sciencedirect.com/science/journal/00404039. |
| URI: | https://dspace.lboro.ac.uk/2134/2891 |
| ISSN: | 0040-4039 |
| Appears in Collections: | Published Articles (Chemistry)
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