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Towards a total synthesis of the manadomanzamine alkaloids: the first asymmetric construction of the pentacyclic indole core
journal contribution
posted on 2007-06-26, 13:45 authored by Steven Allin, Liam J. Duffy, Philip C. Bulman Page, Vickie McKee, Michael J. McKenzieWe report a highly diastereoselective approach for the synthesis of the pentacyclic indole core of the manadomanzamine alkaloid skeleton, with complete control over the relative and absolute stereochemistries at the three contiguous stereocentres at ring positions 1, 10, and 24, from a readily available chiral template.
History
School
- Science
Department
- Chemistry
Citation
ALLIN, S.M. et al, 2007. Towards a total synthesis of the manadomanzamine alkaloids: the first asymmetric construction of the pentacyclic indole core. Tetrahedron Letters, 48(27), pp. 4711-4714Publisher
© ElsevierPublication date
2007Notes
This article was published in the journal, Tetrahedron Letters [© Elsevier]. The definitive version is available at: http://www.sciencedirect.com/science/journal/00404039.ISSN
0040-4039Language
- en