Loughborough University
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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/31895

Title: Some studies with quinazolines and related compounds
Authors: Joshi, Bijaya L.
Issue Date: 1985
Publisher: © Bijaya Luxmi Joshi
Abstract: The thesis reports a study of new methods of modification of the medicinally important quinazoline system by the use of Reissert compounds. Previous attempts to employ this approach have utilized two phase conditions leading only to ring opened products. We have discovered that reaction of 4-phenylquinazoline with an acid chloride and trimethylsilyl cyanide as source of cyanide ion in a single phase system selectively gives a high yield route to the corresponding 1-acyl-2-cyano-1,2-dihydroquinazoline. [Continues.]
Description: A master's thesis submitted in partial fulfilment of the requirements for the award of Master of Philosophy at Loughborough University.
Sponsor: British Council.
URI: https://dspace.lboro.ac.uk/2134/31895
Appears in Collections:MPhil Theses (Chemistry)

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