Cheng_et_al-2018-BMC_Public_Health.pdf (489.58 kB)
Associations of total and type-specific physical activity with mortality in chronic obstructive pulmonary disease: a population-based cohort study
journal contribution
posted on 2018-02-27, 09:33 authored by Sonia Wing Mei Cheng, Zoe McKeough, Jennifer Alison, Sarah Dennis, Mark Hamer, Emmanuel StamatakisBackground: Regular physical activity is recommended for all people with chronic obstructive pulmonary disease
(COPD), but the dose of physical activity required to gain mortality benefit in this population is not yet known. This
aim of this study was to examine the associations of total and type-specific physical activity with mortality risk in
people with COPD.
Methods: People with COPD aged ≥40 years were identified from the 1997 Health Survey for England and the
1998 and 2003 Scottish Health Survey cohorts. Self-reported total physical activity, moderate-vigorous intensity
physical activity (MVPA), walking, domestic physical activity, and sport/exercise were assessed at baseline. Cox
proportional hazards models were used to examine the associations between physical activity and mortality risk.
Results: Two thousand three hundred ninety-eight participants with COPD were included in the analysis and
followed up for a mean 8.5 (SD 3.9) years. For both total physical activity and MVPA, we observed doseresponse
associations with all-cause and cardiovascular disease (CVD) mortality risk, and with respiratory
mortality risk to a lesser extent. Compared to those who reported no physical activity, participants who met
the physical activity guidelines demonstrated the greatest reductions in all-cause (HR 0.56, 95% CI 0.45–0.69),
CVD (HR 0.48, 95% CI 0.32–0.71) and respiratory mortality risk (HR 0.40, 95% CI 0.24–0.67). Participants who
reported a level of physical activity of at least half the dosage recommended by the guidelines also had a
reduced risk of all-cause (HR 0.75, 95% CI 0.56–1.00) and CVD mortality (HR 0.48, 95% CI 0.26–0.88). Doseresponse
associations with mortality risk were demonstrated for walking and sport/exercise, but not domestic
physical activity.
Conclusions: We found a dose-response association between physical activity and all-cause and CVD
mortality risk in people with COPD, with protective effects appearing at levels considerably lower than the
general physical activity recommendations. People with COPD may benefit from engagement in low levels of physical activity, particularly walking and structured exercise.
History
School
- Sport, Exercise and Health Sciences
Published in
BMC Public HealthCitation
CHENG, S.W.M. ... et al, 2018. Associations of total and type-specific physical activity with mortality in chronic obstructive pulmonary disease: a population-based cohort study. BMC Public Health, 18:268Publisher
BioMed Central (© The authors)Version
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2018Notes
© The Author(s). This Open Access article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.ISSN
1471-2458Publisher version
Language
- en