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|Title: ||Associations of physical activity and sedentary behaviour phenotypes with mortality and cardiometabolic risk factors in people with Chronic Obstructive Pulmonary Disease|
|Authors: ||McKeough, Zoe|
Cheng, Sonia Wing Mei
|Keywords: ||Chronic Obstructive Pulmonary Disease|
|Issue Date: ||2018|
|Publisher: ||© Elsevier B.V. on behalf of Australian Physiotherapy Association|
|Citation: ||MCKEOUGH, Z. ... et al, 2018. Associations of physical activity and sedentary behaviour phenotypes with mortality and cardiometabolic risk factors in people with Chronic Obstructive Pulmonary Disease. Journal of Physiotherapy, [in press]|
|Abstract: ||Objectives: To examine the association of four activity phenotypes with mortality and cardiometabolic risk factors in people with Chronic Obstructive Pulmonary Disease (COPD).
Methods: People with COPD aged ≥40 years who were current or ex-smokers were identified from the 2003 Scottish Health Survey and grouped into one of the following activity phenotypes: 1) ‘Couch Potatoes’: insufficiently active with high leisure-based sitting time and/or no domestic physical activity (PA); 2) ‘Light Movers’: insufficiently active with some domestic PA; 3) ‘Sedentary Exercisers’: sufficiently active with high leisure-based sitting time; or 4) ‘Busy Bees’: sufficiently active with low leisure-based sitting time. ‘Sufficiently active’ involved adhering to PA recommendations of ≥ 7.5 metabolic equivalent (MET) hours per week. ‘Low leisure-based sitting time’ was defined as ≤ 200 minutes of recreational screen time per day.
Results: The sample comprised 584 participants (mean age (SD) 63.8 (11.5) years, 52% male). Over 5.5 (1.3) years follow-up, there were 81 all-cause deaths from 433 COPD participants with available data. Compared to the ‘couch potatoes’, there was a reduced risk of all-cause mortality in the ‘busy bees’ (hazard ratio 0.26, 95% confidence interval (CI) 0.11-0.65) with a trend towards a reduction in mortality risk in the other phenotypes (p-trend = 0.005). The odds for diabetes were lower in the ‘busy bees’ compared to the ‘couch potatoes’ (odds ratio 0.14, 95% CI (0.03 to 0.67).
Conclusions: Adhering to PA guidelines and keeping leisure-based sitting time low had a mortality benefit and lower odds of diabetes in people with COPD.|
|Description: ||This paper is closed access until it is published as Open Access in the journal.|
|Version: ||Accepted for publication|
|Publisher Link: ||http://www.journalofphysiotherapy.com/|
|Appears in Collections:||Closed Access (Sport, Exercise and Health Sciences)|
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