Thesis-1986-Lockey.pdf (3.14 MB)
Alkylating derivatives of oestrogens as potentially target-selecting cytotoxic agents
thesis
posted on 2018-03-06, 09:44 authored by Peter M. LockeyThe present work is a study of the structure–activity relationships
and mode of action of oestrogens substituted with alkylating
functions. These compounds are cytotoxic agents potentially selective
for oestrogen-responsive tumours, since the oestrogen part of the
molecule should lead to a concentration in tumour cells thereby
imparting selectivity to the alkylating group. [Continues.]
History
School
- Science
Department
- Chemistry
Publisher
© P.M. LockeyPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
1986Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.Language
- en
