Thesis-1983-AlKhalil.pdf (3.96 MB)
An investigation of the biological and chemical reactivity of aliphatic α-substituted nitro-compounds
thesis
posted on 2018-03-23, 09:53 authored by Suleiman I.H. Al-KhalilA range of 2-substituted-2-nitropropanes (Me2(X)NO2 with X = I, Br,
Cl, NO2, PO3Et2, COMe, CO2Et, SR, SO2R, p-NO2C6H4, p-NO2C6H4N2, CN, SCN,
and N3) have been prepared and tested for antimicrobial activity against a
representative range of micro-organisms. The structure–activity relationship
(S.A.R.) indicates antimicrobial activity of Me2C(X)NO2 in the order of
I > SCN, Br > SR, p-NO2C6H4 > Cl, NO2 > SO2R, N3, CN, PO3Et2, COMe, CO2Et, and p-NO2C6H4N2. [Continues.]
History
School
- Science
Department
- Chemistry
Publisher
© Suleiman Ibrahim Al-KhalilPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
1983Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.Language
- en
