Thesis-1997-Aldabbagh.pdf (4.6 MB)
Radical cyclisations onto imidazoles
thesis
posted on 2018-04-06, 10:14 authored by Fawaz AldabbaghThis thesis describes the development of new pathways towards the synthesis of novel
antimicrobial (and anticancer) agents. Two synthetic protocols based on free radical chemistry
are studied, which are used to access polycyclic heterocyclic compounds of potential biological
importance. Both these procedures involve the generation of radicals using Bu3SnH and AIBN
initiators, and the subsequent intramolecular radical cyclisation onto the imidazole ring. Radical
cyclisations onto benzimidazoles and pyrroles are also described. [Continues.]
Funding
Loughborough University (Postgraduate Research Studentship).
History
School
- Science
Department
- Chemistry
Publisher
© Fawaz AldabbaghPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
1997Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.Language
- en