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Thesis-1997-Aldabbagh.pdf (4.6 MB)

Radical cyclisations onto imidazoles

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thesis
posted on 2018-04-06, 10:14 authored by Fawaz Aldabbagh
This thesis describes the development of new pathways towards the synthesis of novel antimicrobial (and anticancer) agents. Two synthetic protocols based on free radical chemistry are studied, which are used to access polycyclic heterocyclic compounds of potential biological importance. Both these procedures involve the generation of radicals using Bu3SnH and AIBN initiators, and the subsequent intramolecular radical cyclisation onto the imidazole ring. Radical cyclisations onto benzimidazoles and pyrroles are also described. [Continues.]

Funding

Loughborough University (Postgraduate Research Studentship).

History

School

  • Science

Department

  • Chemistry

Publisher

© Fawaz Aldabbagh

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

1997

Notes

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.

Language

  • en

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