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|Title: ||Regulation of metabolic disease-associated inflammation by nutrient sensors|
|Authors: ||Yamashita, Alex S.|
Lira, Fabio S.
Rosa, Jose C.
Festuccia, William T.
Obesity and insulin resistance
|Issue Date: ||2018|
|Publisher: ||Hindawi Publishing Corporation © The Authors|
|Citation: ||YAMASHITA, A.S. ... et al, 2018. Regulation of metabolic disease-associated inflammation by nutrient sensors. Mediators of Inflammation, 2018: 8261432.|
|Abstract: ||Visceral obesity is frequently associated with the development of type 2 diabetes (T2D), a highly prevalent chronic disease that features insulin resistance and pancreatic β-cell dysfunction as important hallmarks. Recent evidence indicates that the chronic, low-grade inflammation commonly associated with visceral obesity plays a major role connecting the excessive visceral fat deposition with the development of insulin resistance and pancreatic β31
cell dysfunction. Herein we review the mechanisms by which nutrients modulate obesity associated inflammation.|
|Description: ||This is an Open Access Article. It is published by the Hindawi Publishing Corporation under the Creative Commons Attribution 4.0 International Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/4.0/. This is the accepted version of the article. It will be replaced by the published version once this is available.|
|Sponsor: ||Funding was provided by Sao Paulo Research Foundation (FAPESP) to ASY (#13/15825-5), TB (#15/22983-1) and to WTF (#10/52191-6 and 15/19530-5).|
|Version: ||Published version|
|Publisher Link: ||https://doi.org/10.1155/2018/8261432|
|Appears in Collections:||Published Articles (Sport, Exercise and Health Sciences)|
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