Thesis-2003-Tebrake.pdf (29.76 MB)
Temperature as a parameter in HPLC optimisation
thesis
posted on 2018-07-13, 10:19 authored by Margret G. TebrakeThis study focused on the capabilities of elevated temperature
chromatography and its potential applications. The effects of
separation temperature on compound retention, selectivity and
efficiency were studied. The change in retention with temperature
was explored using a number of test compound solutions.
A detailed investigation of the importance of system variables like
dead volume, mobile phase composition, different stationary phases,
and temperature control of column and eluent was performed. The
effects of different eluents and different means of temperature
control on the separation selectivity and efficiency were investigated
and results were compared. [Continues.]
History
School
- Science
Department
- Chemistry
Publisher
© Margret G. TebrakePublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2003Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.Language
- en