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Thesis-2003-Tebrake.pdf (29.76 MB)

Temperature as a parameter in HPLC optimisation

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posted on 2018-07-13, 10:19 authored by Margret G. Tebrake
This study focused on the capabilities of elevated temperature chromatography and its potential applications. The effects of separation temperature on compound retention, selectivity and efficiency were studied. The change in retention with temperature was explored using a number of test compound solutions. A detailed investigation of the importance of system variables like dead volume, mobile phase composition, different stationary phases, and temperature control of column and eluent was performed. The effects of different eluents and different means of temperature control on the separation selectivity and efficiency were investigated and results were compared. [Continues.]

History

School

  • Science

Department

  • Chemistry

Publisher

© Margret G. Tebrake

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2003

Notes

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.

Language

  • en

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