MEANWELL, R.J.L. and SHAMA, G., 2005. Direct FTIR assay of streptomycin in agar. Biotechnology letters, 27(20), pp. 1629-1631
Streptomycin titres in samples of agar media on which various species of streptomycetes were cultured were obtained by Fourier Transform Infra Red (FTIR) spectroscopy. Titres were directly comparable to those obtained by bioassay based on Bacillus subtilis inhibition. Analysis by this method could be used to facilitate the isolation of high level antibiotic-producing mutants.