Thesis-1972-Crowther.pdf (3.31 MB)
Studies in sulphoxide chemistry
thesis
posted on 2018-10-29, 15:01 authored by B.C. CrowtherThe effect of further stabilisation on the generation of
sulphoxide carbanions, under milder conditions than those
commonly employed by the generation of dimethylsulphoxide
carbanion, has been briefly investigated. Both dibenzyl
sulphoxide and diphenylsulphinylmethane failed to react
sufficiently under milder conditions.
Attempts to secure the Michael addition of DMSO- to a wide
variety of conjugated systems has proved successful in most cases.
Thus a wide variety of α-phenylcinnamonitriles, formed by
condensation of benzyl cyanide with substituted benzaldehydes,
has given DMSO adducts in good yield. These adducts have
shown interesting features in their mass spectral breakdown
patterns explicable in terms of Hammett coefficients. [Continues.]
Funding
SRC and Boots Pure Drug Company Ltd (CAPS Award).
History
School
- Science
Department
- Chemistry
Publisher
© B. CrowtherPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
1972Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.Language
- en