Thesis-1971-Chhabra.pdf (4.85 MB)
Studies concerning partially reduced nitrogen heterocycles
thesis
posted on 2018-10-30, 17:15 authored by Siri R. ChhabraCarbanion rearrangement studies on selected N-acyl-isoquinoline
and -quinoline Reissert compounds have shown that
alternative intramolecular rearrangements can compete successfully
with the normal 1,2-acyl-migration. The observations have been
rationalised mechanistically and their potential value in
synthesis demonstrated. In particular the formation of a
1-benzoyl-8-hydroxyisoquinoline derivative has been effected
from carbanion rearrangement of the corresponding 8-benzoyloxy
Reissert compound. N-Crotonoylisoquinoline Reissert compound
carbanion and analogous structures have been shown to undergo
a complex reaction in which Michael type attack competes with
the normal migration. [Continues.]
Funding
Loughborough University of Technology.
History
School
- Science
Department
- Chemistry
Publisher
© Siri Ram ChhabraPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
1971Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.Language
- en