Thesis-1973-Gifford.pdf (2.8 MB)
Low-temperature luminescence analysis of drugs and poisons
thesis
posted on 2018-11-02, 12:03 authored by Lawrence A. GiffordIt is the aim of this work to extend the use of phosphorescence as an analytical technique to a number of different classes of drugs and to study any structure–spectral correlations existing between them. Part of the present work is directed towards developing a technique capable of scanning thin-layer chromatograms and measuring the phosphorescence of separated components in situ. The sensitivity of phosphorescence and separatory function of thin-layer chromatography could thus be combined to produce a rapid, sensitive method capable of resolving small quantities of similar compounds, especially drugs and their metabolites, from complex mixtures.
Funding
Medical Research Council.
History
School
- Science
Department
- Chemistry
Publisher
© Lawrence Albert GiffordPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
1973Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of the degree of Doctor of Philosophy at Loughborough University.Language
- en