Thesis-2002-Chung.pdf (1.5 MB)
The use of unsaturated iodine compounds as building blocks in heterocyclic synthesis
thesis
posted on 2018-11-22, 15:52 authored by Bellene ChungThis thesis is concerned with the use of unsaturated iodine compounds as building
blocks in heterocyclic synthesis.
The first investigation involved the use of 1,1-diiodo-2,2-dinitroethylene in
developing a new synthetic route to highly functionalised iodonitroindolizine
heterocycles. Although this new type of ring-formation was successful, the yields of the
iodonitroindolizine derivatives obtained were low.
The structure of one derivative was proved by X-ray crystallography. The reaction
was extended successfully to isoquinolinium salts, but quinolinium salts did not undergo
the reaction.
The second area investigated was the use of trimethylsilylalkynyliodonium triflate
in building new nitrogen and iodine containing heterocycles via alkylidene carbene
insertion reactions. Unfortunately, the studies with iodonium salts have met with little
success.
History
School
- Science
Department
- Chemistry
Publisher
© BeIlene ChungPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2002Notes
A Master's Thesis. Submitted in partial fulfilment of the requirements for the award of the degree of Master of Philosophy at Loughborough University.Language
- en