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The use of unsaturated iodine compounds as building blocks in heterocyclic synthesis

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posted on 2018-11-22, 15:52 authored by Bellene Chung
This thesis is concerned with the use of unsaturated iodine compounds as building blocks in heterocyclic synthesis. The first investigation involved the use of 1,1-diiodo-2,2-dinitroethylene in developing a new synthetic route to highly functionalised iodonitroindolizine heterocycles. Although this new type of ring-formation was successful, the yields of the iodonitroindolizine derivatives obtained were low. The structure of one derivative was proved by X-ray crystallography. The reaction was extended successfully to isoquinolinium salts, but quinolinium salts did not undergo the reaction. The second area investigated was the use of trimethylsilylalkynyliodonium triflate in building new nitrogen and iodine containing heterocycles via alkylidene carbene insertion reactions. Unfortunately, the studies with iodonium salts have met with little success.

History

School

  • Science

Department

  • Chemistry

Publisher

© BeIlene Chung

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2002

Notes

A Master's Thesis. Submitted in partial fulfilment of the requirements for the award of the degree of Master of Philosophy at Loughborough University.

Language

  • en

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