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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/36290

Title: A computational study of mechanical performance of bioresorbable polymeric stents with design variations
Authors: Qiu, Tianyang
Zhao, Liguo
Song, Mo
Keywords: Bioresorbable polymeric stents
Stent expansion
Recoiling and dogboning
Fatigue life
Finite element
Issue Date: 2018
Publisher: Springer Verlag
Citation: QIU, T., ZHAO, L. and SONG, M., 2018. A computational study of mechanical performance of bioresorbable polymeric stents with design variations. Cardiovascular Engineering and Technology, [in press].
Abstract: Purpose: The study compared the mechanical behavior of bioresorbable polymeric stents with various designs during deployment, and investigated their fatigue performance under pulsatile blood pressure loading. Methods: Finite element simulations have been carried out to compare the mechanical performance of four bioresorbable polymeric stents, i.e., Absorb, Elixir, Igaki-Tamai and RevaMedical, during deployment in diseased artery. Tri-folded balloon was modelled to expand the crimped stent onto the three-layered arterial wall with plaque. Cyclic diastolic-systolic pressure loading was applied to both stent and arterial wall to study fatigue behavior. Results: Stents with larger U-bend and longer axial strut demonstrate more flexibility but suffer from severe dogboning and recoiling effects. Stress concentrations in the stent, as well as in the plaque and artery, are higher for stents designed with increased rigidity such as those with smaller U-bends and shorter axial struts. Simulations of fatigue deformation for Elixir stent demonstrate that the U-bends, with high stress concentrations, have a potential risk of fatigue failure under pulsatile systolic-diastolic blood pressure as opposed to the counter metallic stents which are normally free of fatigue failure. Conclusion: The structural behaviour of bioresorbable polymeric stent is strongly affected by its design, in terms of expansion, dogboing, recoiling and stress distribution during the deployment process.
Description: This paper is closed access until 12 months after the date of publication.
Sponsor: LG Zhao acknowledge the support from the British Heart Foundation (Grant number: FS/15/21/31424; Title: Towards controlling the mechanical performance of polymeric bioresorbable vascular scaffold during biodegradation) and the Royal Society of UK (Grant number: IE160066; Title: Evaluating the Performance of Additively Manufactured Endovascular Scaffolds).
Version: Accepted for publication
URI: https://dspace.lboro.ac.uk/2134/36290
Publisher Link: https://www.springer.com/engineering/biomedical+engineering/journal/13239
ISSN: 1869-408X
Appears in Collections:Closed Access (Materials)

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