STILLWELL, M.T....et al., 2009. Low pressure microfilter design aspects and filtration performance. Separation Science and Technology, 44 (11) pp. 2541 - 2558.
A microfilter should retain micron sized material yet provide minimal resistance to
liquid flow. A slotted pore surface microfilter was oscillated whilst filtering yeast cells
under constant rate. At shear rates over 7760 s-1, a pore blocking model fitted the
data. The operating pressure was very low (<1000 Pa), but particle retention was
limited by the 4 micron pore slot width. A sintered glass micro-bead coating improved
yeast rejection: 95% at 1.7 microns at a shear rate of 5000 s-1, with a 1.2 kPa
transmembrane pressure. Two models were validated to assist with the design of
future micro-bead coatings constructed from spherical particles.