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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/5654

Title: Comparison of external bulk video imaging with focused beam reflectance measurement and ultra-violet visible spectroscopy for metastable zone identification in food and pharmaceutical crystallization processes
Authors: Simon, Levente L.
Nagy, Zoltan K.
Hungerbuhler, Konrad
Issue Date: 2009
Publisher: © Elsevier
Citation: SIMON, L.L., NAGY, Z.K. and HUNGERBUHLER, K., 2009. Comparison of external bulk video imaging with focused beam reflectance measurement and ultra violet-visible spectroscopy for metastable zone identification in food and pharmaceutical crystallization processes. Chemical Engineering Science, 64 (14), pp. 3344-3351.
Abstract: The purpose of the paper is twofold: it describes the proof of concept of the newly introduced bulk video imaging (BVI) method and it presents the comparison with existing process analytical technologies (PAT) such as focused beam reflectance measurement (FBRM) and ultra violet/visible (UV/Vis) spectroscopy. While the latter two sample the system in small volumes closely to the probe, the BVI approach monitors the entire or large parts of the crystallizer volume. The BVI method is proposed as a complementary noninvasive PAT tool and it is shown that it is able to detect the boundaries of the metastable zone with comparable or better performance than the FBRM and UV/VIS probes.
Description: This is a journal article. It was published in the Chemical Engineering Journal [© Elsevier] and the definitive version is available www.elsevier.com/locate/ces
Version: Accepted for publication
DOI: 10.1016/j.ces.2009.04.016
URI: https://dspace.lboro.ac.uk/2134/5654
ISSN: 1385-8947
Appears in Collections:Published Articles (Chemical Engineering)

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